Memory Systems and the Addicted Brain

Memory Systems and the Addicted Brain

The view that anatomically distinct memory systems differentially contribute to the development of drug addiction and relapse has received extensive support. The present brief review revisits this hypothesis as it was originally proposed 20 years ago (1) and highlights several recent developments. Extensive research employing a variety of animal learning paradigms indicates that dissociable neu...

The Addicted Brain

example is inflammation: perhaps the simplest form of pathology. It has well defined characteristics which, for many of the old continent, were described in latin: rubor, tumor, calor, dolor, and functio lesa. When these characteristics are present, the pathology/disease can be diagnosed. If it occurs in the lung it will indicate pneumonia, in the kidney nephritis etc. Likewise, a brain chronic...

The addicted brain.

ERIC J. NESTLER and ROBERT C. MALENKA study the molecular basis of drug addiction. Nestler, professor in and chair of the department of psychiatry at the University of Texas Southwestern Medical Center at Dallas, was elected to the Institute of Medicine in 1998. Malenka, professor of psychiatry and behavioral sciences at the Stanford University School of Medicine, joined the faculty there after...

Imaging the Addicted Human Brain

Modern imaging techniques enable researchers to observe drug actions and consequences as they occur and persist in the brains of abusing and addicted individuals. This article presents the five most commonly used techniques, explains how each produces images, and describes how researchers interpret them. The authors give examples of key findings illustrating how each technique has extended and ...

Editorial: Memory Systems of the Addicted Brain: The Underestimated Role of Cognitive Biases in Addiction and Its Treatment